Leon Shargel, Andrew B.C. Yu, Susanna Wu-Pong Shargel, Leon 1941- creator author. Yu, Andrew B. C. 1945- Wu-Pong, Susanna. text bibliography nyu 2012 6th ed. monographic eng

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782 p ; 25 cm. |a Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease. Includes bibliographical references and index. Biopharmaceutics Pharmacokinetics Biopharmaceutics Models, Chemical Pharmacokinetics RM301.4 .S52 2012 9780071603935 (hardcover : alk. paper) 007160393X (hardcover : alk. paper) IQ-NaUA 110512 20221101064410.0 ara